Cargando…

miR-424-5p regulates apoptosis and cell proliferation via targeting Bcl2 in nucleus pulposus cells

miRNAs play an important role in the pathogenesis of intervertebral disc degeneration (IDD). The role and the underlying mechanism of miR-424-5p in human nucleus pulposus (NP) are still unknown. We aimed to explore the role of miR-424-5p in IDD. Real-time PCR was used to detect the expression of miR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Hua-tuo, Xu, Yong-qing, Wang, Hai, Zhang, Xu-lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Molecular Cellular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7651851/ https://www.ncbi.nlm.nih.gov/pubmed/33209193 http://dx.doi.org/10.1080/19768354.2020.1775699

Ejemplares similares

miR-573 regulates cell proliferation and apoptosis by targeting Bax in nucleus pulposus cells
por: Wang, Rui, et al.
Publicado: (2019)

miR-222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl-2
por: Wang, Wei, et al.
Publicado: (2019)

Expression of miR-195 and its target gene Bcl-2 in human intervertebral disc degeneration and their effects on nucleus pulposus cell apoptosis
por: Lin, Xue-Lin, et al.
Publicado: (2021)

Upregulating miR-637 aggravates endoplasmic reticulum stress-induced apoptosis in gastric cancer cells by suppressing Calreticulin
por: Kong, Qingli, et al.
Publicado: (2020)

MiR-210 Up-Regulation Inhibits Proliferation and Induces Apoptosis in Glioma Cells by Targeting SIN3A
por: Shang, Chao, et al.
Publicado: (2014)

Degenerative Nucleus Pulposus Cells Derived Exosomes Promoted Cartilage Endplate Cells Apoptosis and Aggravated Intervertebral Disc Degeneration
por: Feng, Xiaofei, et al.
Publicado: (2022)

MiR-98 Protects Nucleus Pulposus Cells against Apoptosis by Targeting TRAIL in Cervical Intervertebral Disc Degeneration
por: Xu, Shimin, et al.
Publicado: (2022)

miR-21 Promotes Human Nucleus Pulposus Cell Proliferation through PTEN/AKT Signaling
por: Liu, Hongzhe, et al.
Publicado: (2014)

MiR-27a Regulates Apoptosis in Nucleus Pulposus Cells by Targeting PI3K
por: Liu, Gang, et al.
Publicado: (2013)

Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells
por: Lian, Chengjie, et al.
Publicado: (2017)

Induction Function of miR-126 in Survival and Proliferation in Neural Stem Cells
por: Zhang, Qijun, et al.
Publicado: (2015)

KAT5 Negatively regulates the proliferation of prostate cancer LNCaP cells via the caspase 3-dependent apoptosis pathway
por: Kim, Chul-Hong, et al.
Publicado: (2019)

MiR-506 Over-Expression Inhibits Proliferation and Metastasis of Breast Cancer Cells
por: Yu, Fei, et al.
Publicado: (2015)

Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival
por: Lufkin, Leon, et al.
Publicado: (2022)

Polyphyllin I suppressed the apoptosis of intervertebral disc nucleus pulposus cells induced by IL-1β by miR-503-5p/Bcl-2 axis
por: Yuan, Lei, et al.
Publicado: (2023)

LncRNA‐RMRP promotes nucleus pulposus cell proliferation through regulating miR‐206 expression
por: Wang, Xuesong, et al.
Publicado: (2018)

MiR-502 Suppresses TNF-α-Induced Nucleus Pulposus Cell Apoptosis by Targeting TARF2
por: Guo, Zhao, et al.
Publicado: (2021)

miR-4478 Accelerates Nucleus Pulposus Cells Apoptosis Induced by Oxidative Stress by Targeting MTH1
por: Zhang, Jiafang, et al.
Publicado: (2023)

LncRNA AK001796 promotes cell proliferation via acting as a ceRNA of miR-150 in hepatocellular carcinoma
por: Xu, Rui, et al.
Publicado: (2023)

Glucose insult elicits hyperactivation of cancer stem cells through miR-424–cdc42–prdm14 signalling axis
por: Nandy, Sushmita Bose, et al.
Publicado: (2017)

miR-122 promotes diabetic retinopathy through targeting TIMP3
por: Wang, Mingliang, et al.
Publicado: (2020)

Survivin is expressed in degenerated nucleus pulposus cells and is involved in proliferation and the prevention of apoptosis in vitro
por: LIN, YAZHOU, et al.
Publicado: (2016)

ABT-737, a small molecule Bcl-2/Bcl-xL antagonist, increases antimitotic-mediated apoptosis in human prostate cancer cells
por: Parrondo, Ricardo, et al.
Publicado: (2013)

miR-144 Potentially Suppresses Proliferation and Migration of Ovarian Cancer Cells by Targeting RUNX1
por: Han, Shichao, et al.
Publicado: (2018)

A Review on the Role of miR-1290 in Cell Proliferation, Apoptosis and Invasion
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

MiR-29 Induces K562 Cell Apoptosis by Down-Regulating FoxM1
por: Wang, Xiaofang, et al.
Publicado: (2015)

Knockdown of miR-222 inhibits inflammation and the apoptosis of LPS-stimulated human intervertebral disc nucleus pulposus cells
por: Zhang, Yang, et al.
Publicado: (2019)

MiR-140 promotes the progression of intracranial aneurysms by targeting BCL2L2
por: Deng, Jun, et al.
Publicado: (2022)

CRISPR/dCas9-Mediated Parkin Inhibition Impairs Mitophagy and Aggravates Apoptosis of Rat Nucleus Pulposus Cells Under Oxidative Stress
por: Lan, Tao, et al.
Publicado: (2021)

Effect of Fas and Bcl-2 DNA Damages Response Expression in Stem Cells on Apoptosis of Nucleus Pulposus of Intervertebral Disc
por: Zhang, Hui, et al.
Publicado: (2023)

FENDRR Sponges miR-424-5p to Inhibit Cell Proliferation, Migration and Invasion in Colorectal Cancer
por: Cheng, Chuan, et al.
Publicado: (2020)

MiR-15b can target insulin receptor to regulate hepatic insulin signaling in mice
por: Li, Wei-Dong, et al.
Publicado: (2019)

miR-424(322)-5p targets Ezh1 to inhibit the proliferation and differentiation of myoblasts : miR-424(322)-5p regulates the proliferation and differentiation of myoblasts
por: Yue, Yongqi, et al.
Publicado: (2023)

Knockdown of miR-660 protects nucleus pulposus cells from TNF-a-induced apoptosis by targeting serum amyloid A1
por: Zhang, Hao Jie, et al.
Publicado: (2020)

PRDX6 regulates the H2O2 and blue light-induced APRE-19 cell apoptosis via down-regulating and interacting with RARA
por: Zha, Xu, et al.
Publicado: (2019)

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis
por: Xu, Qing, et al.
Publicado: (2012)

Ropivacaine inhibits proliferation, migration, and invasion while inducing apoptosis of glioma cells by regulating the SNHG16/miR-424-5p axis
por: Liu, Rong, et al.
Publicado: (2020)

PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells
por: Zhang, Zhenlei, et al.
Publicado: (2022)

Geranium thunbergii extract-induced G1 phase cell cycle arrest and apoptosis in gastric cancer cells
por: Lee, Hana, et al.
Publicado: (2019)

ZNF424 Induces Apoptosis and Inhibits Proliferation in Lung Carcinoma Cells
por: Liu, W., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_245j6pcekllc0ninpoe3skt8jc