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Single Agent and Synergistic Activity of Maritoclax with ABT-263 in Nasopharyngeal Carcinoma (NPC) Cell Lines

The BCL-2 anti-apoptotic proteins are over-expressed in many cancers and hence are attractive therapeutic targets. In this study, we tested the sensitivity of two Nasopharyngeal Carcinoma (NPC) cell lines HK1 and C666-1 to Maritoclax, which is reported to repress anti-apoptotic protein MCL-1 and BH3...

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Detalles Bibliográficos
Autores principales: Xiang, Benedict Lian Shi, Kwok-Wai, Lo, Soo-Beng, Alan Khoo, Mohana-Kumaran, Nethia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Penerbit Universiti Sains Malaysia 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652248/
https://www.ncbi.nlm.nih.gov/pubmed/33214852
http://dx.doi.org/10.21315/tlsr2020.31.3.1

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