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Single Agent and Synergistic Activity of Maritoclax with ABT-263 in Nasopharyngeal Carcinoma (NPC) Cell Lines
The BCL-2 anti-apoptotic proteins are over-expressed in many cancers and hence are attractive therapeutic targets. In this study, we tested the sensitivity of two Nasopharyngeal Carcinoma (NPC) cell lines HK1 and C666-1 to Maritoclax, which is reported to repress anti-apoptotic protein MCL-1 and BH3...
Autores principales: | Xiang, Benedict Lian Shi, Kwok-Wai, Lo, Soo-Beng, Alan Khoo, Mohana-Kumaran, Nethia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Penerbit Universiti Sains Malaysia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652248/ https://www.ncbi.nlm.nih.gov/pubmed/33214852 http://dx.doi.org/10.21315/tlsr2020.31.3.1 |
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