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Anxiety, depression, and stress in Korean patients with chronic urticaria

BACKGROUND/AIMS: Emotional distress is thought to cause or maintain chronic urticaria (CU). We aimed to investigate the presence of anxiety, depression, and stress in Korean adult CU patients and to explore their potential impact on treatment. METHODS: We enrolled 79 CU patients and a disease contro...

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Autores principales: Choi, Gil-Soon, Nam, Young-Hee, Park, Chan-Sun, Kim, Mi-Yeong, Jo, Eun-Jung, Park, Hye-Kyung, Kim, Hee-Kyoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652653/
https://www.ncbi.nlm.nih.gov/pubmed/32450676
http://dx.doi.org/10.3904/kjim.2019.320
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author Choi, Gil-Soon
Nam, Young-Hee
Park, Chan-Sun
Kim, Mi-Yeong
Jo, Eun-Jung
Park, Hye-Kyung
Kim, Hee-Kyoo
author_facet Choi, Gil-Soon
Nam, Young-Hee
Park, Chan-Sun
Kim, Mi-Yeong
Jo, Eun-Jung
Park, Hye-Kyung
Kim, Hee-Kyoo
author_sort Choi, Gil-Soon
collection PubMed
description BACKGROUND/AIMS: Emotional distress is thought to cause or maintain chronic urticaria (CU). We aimed to investigate the presence of anxiety, depression, and stress in Korean adult CU patients and to explore their potential impact on treatment. METHODS: We enrolled 79 CU patients and a disease control group comprising 39 persistent asthma patients. The Hospital Anxiety and Depression Scale (HADS) was used to evaluate depression and anxiety. Stress and quality of life (QoL) were assessed by Stress Response Inventory and CU-QoL questionnaires. The sociodemographic and clinical data such as urticaria activity score (UAS-15, UAS-6) were obtained. RESULTS: The prevalence of depression and anxiety based on the HADS were 48.1% and 38.0%. Although the prevalence of anxiety didn’t differ between the CU and asthma patients, depression was significantly more prevalent in the CU patients (48.1% vs. 28.2%). Stress tended to be lower in CU patients. Anxiety, depression, and stress exhibited negative correlations with QoL. Anxiety showed significant correlation with UAS-6 and pruritus-visual analog scale (VAS; r = 0.256, r = 0.272, p < 0.05, respectively); depression correlated with sleep difficulty-VAS (r = 0.261, p < 0.05). Stress was associated with UAS-15, UAS-6, pruritus-VAS, and sleep difficulty-VAS (r = 0.251, r = 0.317, r = 0.302, r = 0.258, p < 0.05, respectively). CONCLUSIONS: The current study first presented that Korean CU patients frequently have anxiety and depression, which affect their QoL and demonstrated that anxiety, depression, and stress had different effects on sleep difficulty, pruritus, and urticaria severity in Korean CU patients.
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spelling pubmed-76526532020-11-18 Anxiety, depression, and stress in Korean patients with chronic urticaria Choi, Gil-Soon Nam, Young-Hee Park, Chan-Sun Kim, Mi-Yeong Jo, Eun-Jung Park, Hye-Kyung Kim, Hee-Kyoo Korean J Intern Med Original Article BACKGROUND/AIMS: Emotional distress is thought to cause or maintain chronic urticaria (CU). We aimed to investigate the presence of anxiety, depression, and stress in Korean adult CU patients and to explore their potential impact on treatment. METHODS: We enrolled 79 CU patients and a disease control group comprising 39 persistent asthma patients. The Hospital Anxiety and Depression Scale (HADS) was used to evaluate depression and anxiety. Stress and quality of life (QoL) were assessed by Stress Response Inventory and CU-QoL questionnaires. The sociodemographic and clinical data such as urticaria activity score (UAS-15, UAS-6) were obtained. RESULTS: The prevalence of depression and anxiety based on the HADS were 48.1% and 38.0%. Although the prevalence of anxiety didn’t differ between the CU and asthma patients, depression was significantly more prevalent in the CU patients (48.1% vs. 28.2%). Stress tended to be lower in CU patients. Anxiety, depression, and stress exhibited negative correlations with QoL. Anxiety showed significant correlation with UAS-6 and pruritus-visual analog scale (VAS; r = 0.256, r = 0.272, p < 0.05, respectively); depression correlated with sleep difficulty-VAS (r = 0.261, p < 0.05). Stress was associated with UAS-15, UAS-6, pruritus-VAS, and sleep difficulty-VAS (r = 0.251, r = 0.317, r = 0.302, r = 0.258, p < 0.05, respectively). CONCLUSIONS: The current study first presented that Korean CU patients frequently have anxiety and depression, which affect their QoL and demonstrated that anxiety, depression, and stress had different effects on sleep difficulty, pruritus, and urticaria severity in Korean CU patients. The Korean Association of Internal Medicine 2020-11 2020-05-27 /pmc/articles/PMC7652653/ /pubmed/32450676 http://dx.doi.org/10.3904/kjim.2019.320 Text en Copyright © 2020 The Korean Association of Internal Medicine This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Choi, Gil-Soon
Nam, Young-Hee
Park, Chan-Sun
Kim, Mi-Yeong
Jo, Eun-Jung
Park, Hye-Kyung
Kim, Hee-Kyoo
Anxiety, depression, and stress in Korean patients with chronic urticaria
title Anxiety, depression, and stress in Korean patients with chronic urticaria
title_full Anxiety, depression, and stress in Korean patients with chronic urticaria
title_fullStr Anxiety, depression, and stress in Korean patients with chronic urticaria
title_full_unstemmed Anxiety, depression, and stress in Korean patients with chronic urticaria
title_short Anxiety, depression, and stress in Korean patients with chronic urticaria
title_sort anxiety, depression, and stress in korean patients with chronic urticaria
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652653/
https://www.ncbi.nlm.nih.gov/pubmed/32450676
http://dx.doi.org/10.3904/kjim.2019.320
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