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MGMIN: A Normalization Method for Correcting Probe Design Bias in Illumina Infinium HumanMethylation450 BeadChips

The Illumina Infinium HumanMethylation450 Beadchips have been widely utilized in epigenome-wide association studies (EWAS). However, the existing two types of probes (type I and type II), with the distribution of measurements of probes and dynamic range different, may bias downstream analyses. Here,...

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Detalles Bibliográficos
Autores principales: Wang, Zhenxing, Liu, Yongzhuang, Wang, Yadong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652792/
https://www.ncbi.nlm.nih.gov/pubmed/33193611
http://dx.doi.org/10.3389/fgene.2020.538492