The influence of cardiac output on propofol and fentanyl pharmacokinetics and pharmacodynamics in patients undergoing abdominal aortic surgery

Cardiac output (CO) is expected to affect elimination and distribution of highly extracted and perfusion rate-limited drugs. This work was undertaken to quantify the effect of CO measured by the pulse pressure method on pharmacokinetics and pharmacodynamics of propofol and fentanyl administrated dur...

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Detalles Bibliográficos
Autores principales: Bienert, Agnieszka, Sobczyński, Paweł, Młodawska, Katarzyna, Hartmann-Sobczyńska, Roma, Grześkowiak, Edmund, Wiczling, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652808/
https://www.ncbi.nlm.nih.gov/pubmed/32840723
http://dx.doi.org/10.1007/s10928-020-09712-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652808/
https://www.ncbi.nlm.nih.gov/pubmed/32840723
http://dx.doi.org/10.1007/s10928-020-09712-1

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