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Somatic copy number gains in MYC, BCL2, and BCL6 identifies a subset of aggressive alternative-DH/TH DLBCL patients
Double/triple hit lymphoma (DH/TH), known as high-grade B-cell lymphoma (HGBL), is an aggressive diffuse large B cell lymphoma (DLBCL), defined as having concurrent MYC, BCL2, and/or BCL6 gene rearrangements. While gene rearrangements represent significant genetic events in cancer, copy number alter...
Autores principales: | Krull, Jordan E., Wenzl, Kerstin, Hartert, Keenan T., Manske, Michelle K., Sarangi, Vivekananda, Maurer, Matthew J., Larson, Melissa C., Nowakowski, Grzegorz S., Ansell, Stephen M., McPhail, Ellen, Habermann, Thomas M., Link, Brian K., King, Rebecca L., Cerhan, James R., Novak, Anne J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652824/ https://www.ncbi.nlm.nih.gov/pubmed/33168821 http://dx.doi.org/10.1038/s41408-020-00382-3 |
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