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Evaluation of urinary inflammatory index in rapid screening of urinary tract infection

The objective of this study was to assess the diagnosis value of urinary inflammatory index (UII) and systemic immune-inflammation index (SII) for UTI. Nine inflammatory indexes including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, SII and six UIIs were calculated for Receiver oper...

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Autores principales: Gu, Wanjian, Huang, Weizhou, Zhang, Jie, Qian, Shining, Cao, Huiling, Ge, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652836/
https://www.ncbi.nlm.nih.gov/pubmed/33168850
http://dx.doi.org/10.1038/s41598-020-76352-3
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author Gu, Wanjian
Huang, Weizhou
Zhang, Jie
Qian, Shining
Cao, Huiling
Ge, Liang
author_facet Gu, Wanjian
Huang, Weizhou
Zhang, Jie
Qian, Shining
Cao, Huiling
Ge, Liang
author_sort Gu, Wanjian
collection PubMed
description The objective of this study was to assess the diagnosis value of urinary inflammatory index (UII) and systemic immune-inflammation index (SII) for UTI. Nine inflammatory indexes including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, SII and six UIIs were calculated for Receiver operating characteristic curve analysis to select which one is suitable for the screening of UTIs or distinguishing the types of bacteria. UII3, which calculated from leucocyte esterase (LE), nitrite, white blood cells and bacteria, was preferentially used as an indicator for the diagnosis of UTI when the threshold was set at 0.53. UII2 was more suitable for the distinction between groups when the cutoff is set to 0.94. Appropriate urinary inflammation index calculated by rapid urinalysis of urine dipstick and urine sediment can help us to predict urinary tract infection and bacterial type, and reduce the workload and costs of urine culture.
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spelling pubmed-76528362020-11-12 Evaluation of urinary inflammatory index in rapid screening of urinary tract infection Gu, Wanjian Huang, Weizhou Zhang, Jie Qian, Shining Cao, Huiling Ge, Liang Sci Rep Article The objective of this study was to assess the diagnosis value of urinary inflammatory index (UII) and systemic immune-inflammation index (SII) for UTI. Nine inflammatory indexes including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, SII and six UIIs were calculated for Receiver operating characteristic curve analysis to select which one is suitable for the screening of UTIs or distinguishing the types of bacteria. UII3, which calculated from leucocyte esterase (LE), nitrite, white blood cells and bacteria, was preferentially used as an indicator for the diagnosis of UTI when the threshold was set at 0.53. UII2 was more suitable for the distinction between groups when the cutoff is set to 0.94. Appropriate urinary inflammation index calculated by rapid urinalysis of urine dipstick and urine sediment can help us to predict urinary tract infection and bacterial type, and reduce the workload and costs of urine culture. Nature Publishing Group UK 2020-11-09 /pmc/articles/PMC7652836/ /pubmed/33168850 http://dx.doi.org/10.1038/s41598-020-76352-3 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Gu, Wanjian
Huang, Weizhou
Zhang, Jie
Qian, Shining
Cao, Huiling
Ge, Liang
Evaluation of urinary inflammatory index in rapid screening of urinary tract infection
title Evaluation of urinary inflammatory index in rapid screening of urinary tract infection
title_full Evaluation of urinary inflammatory index in rapid screening of urinary tract infection
title_fullStr Evaluation of urinary inflammatory index in rapid screening of urinary tract infection
title_full_unstemmed Evaluation of urinary inflammatory index in rapid screening of urinary tract infection
title_short Evaluation of urinary inflammatory index in rapid screening of urinary tract infection
title_sort evaluation of urinary inflammatory index in rapid screening of urinary tract infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652836/
https://www.ncbi.nlm.nih.gov/pubmed/33168850
http://dx.doi.org/10.1038/s41598-020-76352-3
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