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Evaluation of urinary inflammatory index in rapid screening of urinary tract infection
The objective of this study was to assess the diagnosis value of urinary inflammatory index (UII) and systemic immune-inflammation index (SII) for UTI. Nine inflammatory indexes including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, SII and six UIIs were calculated for Receiver oper...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652836/ https://www.ncbi.nlm.nih.gov/pubmed/33168850 http://dx.doi.org/10.1038/s41598-020-76352-3 |
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author | Gu, Wanjian Huang, Weizhou Zhang, Jie Qian, Shining Cao, Huiling Ge, Liang |
author_facet | Gu, Wanjian Huang, Weizhou Zhang, Jie Qian, Shining Cao, Huiling Ge, Liang |
author_sort | Gu, Wanjian |
collection | PubMed |
description | The objective of this study was to assess the diagnosis value of urinary inflammatory index (UII) and systemic immune-inflammation index (SII) for UTI. Nine inflammatory indexes including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, SII and six UIIs were calculated for Receiver operating characteristic curve analysis to select which one is suitable for the screening of UTIs or distinguishing the types of bacteria. UII3, which calculated from leucocyte esterase (LE), nitrite, white blood cells and bacteria, was preferentially used as an indicator for the diagnosis of UTI when the threshold was set at 0.53. UII2 was more suitable for the distinction between groups when the cutoff is set to 0.94. Appropriate urinary inflammation index calculated by rapid urinalysis of urine dipstick and urine sediment can help us to predict urinary tract infection and bacterial type, and reduce the workload and costs of urine culture. |
format | Online Article Text |
id | pubmed-7652836 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-76528362020-11-12 Evaluation of urinary inflammatory index in rapid screening of urinary tract infection Gu, Wanjian Huang, Weizhou Zhang, Jie Qian, Shining Cao, Huiling Ge, Liang Sci Rep Article The objective of this study was to assess the diagnosis value of urinary inflammatory index (UII) and systemic immune-inflammation index (SII) for UTI. Nine inflammatory indexes including neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, SII and six UIIs were calculated for Receiver operating characteristic curve analysis to select which one is suitable for the screening of UTIs or distinguishing the types of bacteria. UII3, which calculated from leucocyte esterase (LE), nitrite, white blood cells and bacteria, was preferentially used as an indicator for the diagnosis of UTI when the threshold was set at 0.53. UII2 was more suitable for the distinction between groups when the cutoff is set to 0.94. Appropriate urinary inflammation index calculated by rapid urinalysis of urine dipstick and urine sediment can help us to predict urinary tract infection and bacterial type, and reduce the workload and costs of urine culture. Nature Publishing Group UK 2020-11-09 /pmc/articles/PMC7652836/ /pubmed/33168850 http://dx.doi.org/10.1038/s41598-020-76352-3 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Gu, Wanjian Huang, Weizhou Zhang, Jie Qian, Shining Cao, Huiling Ge, Liang Evaluation of urinary inflammatory index in rapid screening of urinary tract infection |
title | Evaluation of urinary inflammatory index in rapid screening of urinary tract infection |
title_full | Evaluation of urinary inflammatory index in rapid screening of urinary tract infection |
title_fullStr | Evaluation of urinary inflammatory index in rapid screening of urinary tract infection |
title_full_unstemmed | Evaluation of urinary inflammatory index in rapid screening of urinary tract infection |
title_short | Evaluation of urinary inflammatory index in rapid screening of urinary tract infection |
title_sort | evaluation of urinary inflammatory index in rapid screening of urinary tract infection |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652836/ https://www.ncbi.nlm.nih.gov/pubmed/33168850 http://dx.doi.org/10.1038/s41598-020-76352-3 |
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