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Platelet PD-L1 suppresses anti-cancer immune cell activity in PD-L1 negative tumors
Strategies that interfere with the binding of the receptor programmed cell death protein-1 (PD-1) to programmed death ligand-1 (PD-L1) have shown marked efficacy against many advanced cancers, including those that are negative for PD-L1. Precisely why patients with PD-L1 negative tumors respond to P...
Autores principales: | Zaslavsky, Alexander B., Adams, M. P., Cao, X., Maj, T., Choi, J. E., Stangl-Kremser, J., Patel, S., Putelo, A., Lee, S. K., Nallandhighal, S., Kasputis, A., Alva, A., Lew, M., Qin, A., Mehra, R., Morgan, T. M., Salami, S. S., Reichert, Z., Udager, A., Zou, W., Palapattu, Ganesh S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652857/ https://www.ncbi.nlm.nih.gov/pubmed/33168847 http://dx.doi.org/10.1038/s41598-020-76351-4 |
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