Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness

Eighty-two patients seeking consultation for long-term sequalae after suspected tick-borne illness were consecutively tested for Borrelia miyamotoi antibodies using a recombinant glycerophosphodiester phosphodiesterase (GlpQ) enzyme immunoassay. Twenty-one of the 82 patients (26%) tested positive on...

Descripción completa

Detalles Bibliográficos
Autores principales: Delaney, Shannon L., Murray, Lilly A., Aasen, Claire E., Bennett, Clair E., Brown, Ellen, Fallon, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652925/
https://www.ncbi.nlm.nih.gov/pubmed/33195313
http://dx.doi.org/10.3389/fmed.2020.567350
_version_ 1783607797229813760
author Delaney, Shannon L.
Murray, Lilly A.
Aasen, Claire E.
Bennett, Clair E.
Brown, Ellen
Fallon, Brian A.
author_facet Delaney, Shannon L.
Murray, Lilly A.
Aasen, Claire E.
Bennett, Clair E.
Brown, Ellen
Fallon, Brian A.
author_sort Delaney, Shannon L.
collection PubMed
description Eighty-two patients seeking consultation for long-term sequalae after suspected tick-borne illness were consecutively tested for Borrelia miyamotoi antibodies using a recombinant glycerophosphodiester phosphodiesterase (GlpQ) enzyme immunoassay. Twenty-one of the 82 patients (26%) tested positive on the GlpQ IgG ELISA. Nearly all of the patients (98%) had no prior B. miyamotoi testing, indicating that clinicians rarely test for this emerging tick-borne pathogen. Compared to patients who solely tested positive for Lyme disease antibodies, patients with B. miyamotoi antibodies presented with significantly more sleepiness and pain. A prospective study is needed to ascertain the relationship between the presence of B. miyamotoi antibodies and persistent symptoms.
format Online
Article
Text
id pubmed-7652925
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-76529252020-11-13 Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness Delaney, Shannon L. Murray, Lilly A. Aasen, Claire E. Bennett, Clair E. Brown, Ellen Fallon, Brian A. Front Med (Lausanne) Medicine Eighty-two patients seeking consultation for long-term sequalae after suspected tick-borne illness were consecutively tested for Borrelia miyamotoi antibodies using a recombinant glycerophosphodiester phosphodiesterase (GlpQ) enzyme immunoassay. Twenty-one of the 82 patients (26%) tested positive on the GlpQ IgG ELISA. Nearly all of the patients (98%) had no prior B. miyamotoi testing, indicating that clinicians rarely test for this emerging tick-borne pathogen. Compared to patients who solely tested positive for Lyme disease antibodies, patients with B. miyamotoi antibodies presented with significantly more sleepiness and pain. A prospective study is needed to ascertain the relationship between the presence of B. miyamotoi antibodies and persistent symptoms. Frontiers Media S.A. 2020-10-27 /pmc/articles/PMC7652925/ /pubmed/33195313 http://dx.doi.org/10.3389/fmed.2020.567350 Text en Copyright © 2020 Delaney, Murray, Aasen, Bennett, Brown and Fallon. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Delaney, Shannon L.
Murray, Lilly A.
Aasen, Claire E.
Bennett, Clair E.
Brown, Ellen
Fallon, Brian A.
Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness
title Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness
title_full Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness
title_fullStr Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness
title_full_unstemmed Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness
title_short Borrelia miyamotoi Serology in a Clinical Population With Persistent Symptoms and Suspected Tick-Borne Illness
title_sort borrelia miyamotoi serology in a clinical population with persistent symptoms and suspected tick-borne illness
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652925/
https://www.ncbi.nlm.nih.gov/pubmed/33195313
http://dx.doi.org/10.3389/fmed.2020.567350
work_keys_str_mv AT delaneyshannonl borreliamiyamotoiserologyinaclinicalpopulationwithpersistentsymptomsandsuspectedtickborneillness
AT murraylillya borreliamiyamotoiserologyinaclinicalpopulationwithpersistentsymptomsandsuspectedtickborneillness
AT aasenclairee borreliamiyamotoiserologyinaclinicalpopulationwithpersistentsymptomsandsuspectedtickborneillness
AT bennettclaire borreliamiyamotoiserologyinaclinicalpopulationwithpersistentsymptomsandsuspectedtickborneillness
AT brownellen borreliamiyamotoiserologyinaclinicalpopulationwithpersistentsymptomsandsuspectedtickborneillness
AT fallonbriana borreliamiyamotoiserologyinaclinicalpopulationwithpersistentsymptomsandsuspectedtickborneillness

Ejemplares similares