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Tear Film Pharmacokinetics and Systemic Absorption Following Topical Administration of 1% Prednisolone Acetate Ophthalmic Suspension in Dogs

The study aimed to determine the tear film pharmacokinetics following topical administration of 1% prednisolone acetate—assessing whether two drops would provide a superior kinetic profile compared to one drop—and to determine the fraction of an eye drop that reaches the systemic circulation in dogs...

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Detalles Bibliográficos
Autores principales: Sebbag, Lionel, Kirner, Nicolette S., Wulf, Larry W., Mochel, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652929/
https://www.ncbi.nlm.nih.gov/pubmed/33195562
http://dx.doi.org/10.3389/fvets.2020.571350