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EZH2 facilitates BMI1-dependent hepatocarcinogenesis through epigenetically silencing microRNA-200c

EZH2, a histone methyltransferase, has been shown to involve in cancer development and progression via epigenetic regulation of tumor suppressor microRNAs, whereas BMI1, a driver of hepatocellular carcinoma (HCC), is a downstream target of these microRNAs. However, it remains unclear whether EZH2 ca...

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Detalles Bibliográficos
Autores principales:	Xu, Leibo, Lin, Junlong, Deng, Wanyu, Luo, Weixin, Huang, Yipei, Liu, Chao-Qun, Zhang, Fa-Peng, Qin, Yu-Fei, Wong, Ping-Pui, Liu, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652937/ https://www.ncbi.nlm.nih.gov/pubmed/33168810 http://dx.doi.org/10.1038/s41389-020-00284-w

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