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Radioimmunotherapy of PANC-1 human pancreatic cancer xenografts in NOD/SCID or NRG mice with Panitumumab labeled with Auger electron emitting, (111)In or β-particle emitting, (177)Lu

BACKGROUND: Epidermal growth factor receptors (EGFR) are overexpressed on > 90% of pancreatic cancers (PnCa) and represent an attractive target for the development of novel therapies, including radioimmunotherapy (RIT). Our aim was to study RIT of subcutaneous (s.c.) PANC-1 human PnCa xenografts...

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Detalles Bibliográficos
Autores principales: Aghevlian, Sadaf, Cai, Zhongli, Hedley, David, Winnik, Mitchell A., Reilly, Raymond M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7652961/
https://www.ncbi.nlm.nih.gov/pubmed/33169241
http://dx.doi.org/10.1186/s41181-020-00111-y

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