Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts

The tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) is highly heterogeneous, fibrotic, and hypovascular, marked by extensive desmoplasia and maintained by the tumor cells, cancer-associated fibroblasts (CAFs) and other stromal cells. There is an urgent need to identify and develop...

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Detalles Bibliográficos
Autores principales: Noel, Pawan, Hussein, Shaimaa, Ng, Serina, Antal, Corina E., Lin, Wei, Rodela, Emily, Delgado, Priscilla, Naveed, Sanna, Downes, Michael, Lin, Yin, Evans, Ronald M., Von Hoff, Daniel D., Han, Haiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653036/
https://www.ncbi.nlm.nih.gov/pubmed/33168807
http://dx.doi.org/10.1038/s41389-020-00285-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653036/
https://www.ncbi.nlm.nih.gov/pubmed/33168807
http://dx.doi.org/10.1038/s41389-020-00285-9

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