FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging

Sarcopenia is characterized by decreased skeletal muscle mass and function with age. Aged muscles have altered lipid compositions; however, the role and regulation of lipids are unknown. Here we report that FABP3 is upregulated in aged skeletal muscles, disrupting homeostasis via lipid remodeling. L...

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Detalles Bibliográficos
Autores principales: Lee, Seung-Min, Lee, Seol Hee, Jung, Youngae, Lee, Younglang, Yoon, Jong Hyun, Choi, Jeong Yi, Hwang, Chae Young, Son, Young Hoon, Park, Sung Sup, Hwang, Geum-Sook, Lee, Kwang-Pyo, Kwon, Ki-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653047/
https://www.ncbi.nlm.nih.gov/pubmed/33168829
http://dx.doi.org/10.1038/s41467-020-19501-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653047/
https://www.ncbi.nlm.nih.gov/pubmed/33168829
http://dx.doi.org/10.1038/s41467-020-19501-6

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