Cargando…

FABP3-mediated membrane lipid saturation alters fluidity and induces ER stress in skeletal muscle with aging

Sarcopenia is characterized by decreased skeletal muscle mass and function with age. Aged muscles have altered lipid compositions; however, the role and regulation of lipids are unknown. Here we report that FABP3 is upregulated in aged skeletal muscles, disrupting homeostasis via lipid remodeling. L...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Seung-Min, Lee, Seol Hee, Jung, Youngae, Lee, Younglang, Yoon, Jong Hyun, Choi, Jeong Yi, Hwang, Chae Young, Son, Young Hoon, Park, Sung Sup, Hwang, Geum-Sook, Lee, Kwang-Pyo, Kwon, Ki-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653047/ https://www.ncbi.nlm.nih.gov/pubmed/33168829 http://dx.doi.org/10.1038/s41467-020-19501-6

Ejemplares similares

A new AMPK isoform mediates glucose-restriction induced longevity non-cell autonomously by promoting membrane fluidity
por: Jeong, Jin-Hyuck, et al.
Publicado: (2023)

Phosphatidylinositol 3‐kinase‐δ controls endoplasmic reticulum membrane fluidity and permeability in fungus‐induced allergic inflammation in mice
por: Lee, Hwa‐Young, et al.
Publicado: (2020)

Regulation of lipid saturation without sensing membrane fluidity
por: Ballweg, Stephanie, et al.
Publicado: (2020)

Urinary Metabolomic Profiling in Streptozotocin-Induced Diabetic Mice after Treatment with Losartan
por: Hyeon, Jin Seong, et al.
Publicado: (2020)

Metabolic Responses to Orientia tsutsugamushi Infection in a Mouse Model
por: Jung, Jeeyoun, et al.
Publicado: (2015)

Metabolic Alterations Associated with Atorvastatin/Fenofibric Acid Combination in Patients with Atherogenic Dyslipidaemia: A Randomized Trial for Comparison with Escalated-Dose Atorvastatin
por: Han, Ji Soo, et al.
Publicado: (2018)

Identification of Potential Biomarkers in the Cervicovaginal Fluid by Metabolic Profiling for Preterm Birth
por: Ansari, AbuZar, et al.
Publicado: (2020)

Urinary Metabolomic Profiling Analysis and Evaluation of the Effect of Ecklonia cava Extract Intake
por: Kim, Juyeon, et al.
Publicado: (2020)

FABP1 and FABP2 as markers of diabetic nephropathy
por: Tsai, I-Ting, et al.
Publicado: (2020)

Lipidomic Profiling of Liver Tissue from Obesity-Prone and Obesity-Resistant Mice Fed a High Fat Diet
por: Nam, Miso, et al.
Publicado: (2015)

Effect of Micro-Scale Er on the Microstructure and Fluidity of ZL205A Alloy
por: Guo, Tingbiao, et al.
Publicado: (2019)

IBF-R Regulates IRE1α Post-Translational Modifications and ER Stress in High-Fat Diet-Induced Obese Mice
por: Lee, Hwa-Young, et al.
Publicado: (2022)

FABP5 as a possible biomarker in atopic march: FABP5-induced Th17 polarization, both in mouse model and human samples
por: Lee, Jungsoo, et al.
Publicado: (2020)

Secondary Metabolite Profiling of Curcuma Species Grown at Different Locations Using GC/TOF and UPLC/Q-TOF MS
por: Lee, Jueun, et al.
Publicado: (2014)

Rapid Characterization and Discovery of Chemical Markers for Discrimination of Xanthii Fructus by Gas Chromatography Coupled to Mass Spectrometry
por: Kim, Hayoung, et al.
Publicado: (2019)

FABP3, FABP4, and heart rate variability among patients with chronic schizophrenia
por: Hung, Wei-Chin, et al.
Publicado: (2023)

Lipidomic profiling reveals free fatty acid alterations in plasma from patients with atrial fibrillation
por: Jung, Youngae, et al.
Publicado: (2018)

Urine myo-inositol as a novel prognostic biomarker for diabetic kidney disease: a targeted metabolomics study using nuclear magnetic resonance
por: Kwon, Soie, et al.
Publicado: (2023)

Fluidity of the body
por: Kothari, Manu, et al.
Publicado: (2014)

Finding Fluidity
por: Kenchington-Evans, Lily
Publicado: (2022)

Gender-Specific Metabolomic Profiling of Obesity in Leptin-Deficient ob/ob Mice by (1)H NMR Spectroscopy
por: Won, Eun-Young, et al.
Publicado: (2013)

Urinary myo-inositol is associated with the clinical outcome in focal segmental glomerulosclerosis
por: An, Jung Nam, et al.
Publicado: (2019)

TRIM11 Negatively Regulates IFNβ Production and Antiviral Activity by Targeting TBK1
por: Lee, Younglang, et al.
Publicado: (2013)

Integrative Pathway Analysis of SNP and Metabolite Data Using a Hierarchical Structural Component Model
por: Jung, Taeyeong, et al.
Publicado: (2022)

microRNA for determining the age-related myogenic capabilities of skeletal muscle
por: Lee, Kwang-Pyo, et al.
Publicado: (2015)

Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway
por: Park, Ki-Sun, et al.
Publicado: (2022)

Fluidity onset in graphene
por: Bandurin, Denis A., et al.
Publicado: (2018)

Systemic Transitional Fluidity
por: Ali, S. Mahmud
Publicado: (2015)

Disrupting enzyme fluidity
por: Anand, Ganesh Srinivasan
Publicado: (2021)

Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells
por: Seo, Jieun, et al.
Publicado: (2020)

Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis
por: Bahar, Entaz, et al.
Publicado: (2017)

PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD–RIG-I–NF-κB axis
por: Kim, Hyun-Kyoung, et al.
Publicado: (2018)

Endothelial cell-derived stem cell factor promotes lipid accumulation through c-Kit-mediated increase of lipogenic enzymes in brown adipocytes
por: Lee, Hyuek Jong, et al.
Publicado: (2023)

Intermittent Fasting Attenuates Metabolic-Dysfunction-Associated Steatohepatitis by Enhancing the Hepatic Autophagy–Lysosome Pathway
por: Kim, Kyung Eun, et al.
Publicado: (2023)

Angiotensin II affects inflammation mechanisms via AMPK-related signalling pathways in HL-1 atrial myocytes
por: Kim, Nami, et al.
Publicado: (2017)

Fabp4-CreER lineage tracing revealstwo distinctive coronary vascular populations
por: He, Lingjuan, et al.
Publicado: (2014)

Enhanced A-FABP expression in visceral fat: potential contributor to the progression of NASH
por: Yoon, Min Yong, et al.
Publicado: (2012)

Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae
por: Reglinski, Katharina, et al.
Publicado: (2020)

Eucommia ulmoides Oliver Extract, Aucubin, and Geniposide Enhance Lysosomal Activity to Regulate ER Stress and Hepatic Lipid Accumulation
por: Lee, Hwa-Young, et al.
Publicado: (2013)

Decrease in membrane fluidity and traction force induced by silica-coated magnetic nanoparticles
por: Shin, Tae Hwan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8b27bor24k5hrh22t1kthu3m18