Mass Cytometry Phenotyping of Human Granulocytes Reveals Novel Basophil Functional Heterogeneity

Basophils, the rarest granulocyte, play critical roles in parasite- and allergen-induced inflammation. We applied mass cytometry (CyTOF) to simultaneously asses 44 proteins to phenotype and functionally characterize neutrophils, eosinophils, and basophils from 19 healthy donors. There was minimal he...

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Detalles Bibliográficos
Autores principales: Vivanco Gonzalez, Nora, Oliveria, John-Paul, Tebaykin, Dmitry, Ivison, Geoffrey T., Mukai, Kaori, Tsai, Mindy M., Borges, Luciene, Nadeau, Kari C., Galli, Stephen J., Tsai, Albert G., Bendall, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653073/
https://www.ncbi.nlm.nih.gov/pubmed/33205028
http://dx.doi.org/10.1016/j.isci.2020.101724

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