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Histone H3K79 demethylation by KDM2B facilitates proper DNA replication through PCNA dissociation from chromatin
OBJECTIVES: The level of histone H3 lysine 79 methylation is regulated by the cell cycle and involved in cell proliferation. KDM2B is an H3K79 demethylase. Proliferating cell nuclear antigen (PCNA) is a component of the DNA replication machinery. This study aimed at elucidating a molecular link betw...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653264/ https://www.ncbi.nlm.nih.gov/pubmed/33029857 http://dx.doi.org/10.1111/cpr.12920 |