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DeepCryoPicker: fully automated deep neural network for single protein particle picking in cryo-EM
BACKGROUND: Cryo-electron microscopy (Cryo-EM) is widely used in the determination of the three-dimensional (3D) structures of macromolecules. Particle picking from 2D micrographs remains a challenging early step in the Cryo-EM pipeline due to the diversity of particle shapes and the extremely low s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653784/ https://www.ncbi.nlm.nih.gov/pubmed/33167860 http://dx.doi.org/10.1186/s12859-020-03809-7 |