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Functional and clinical significance of ROR1 in lung adenocarcinoma

BACKGROUND: Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is normally detectable in embryonic tissues and absent in adult tissues. ROR1 was shown to inhibit apoptosis, potentiate EGFR signaling and reported to be overexpressed and associated with poor prognosis in several tumor models. This...

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Detalles Bibliográficos
Autores principales:	Giovanna, Schiavone, Samantha, Epistolio, Vittoria, Martin, Francesca, Molinari, Jessica, Barizzi, Luca, Mazzucchelli, Milo, Frattini, Luciano, Wannesson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653802/ https://www.ncbi.nlm.nih.gov/pubmed/33172431 http://dx.doi.org/10.1186/s12885-020-07587-6

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