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Oxidation resistance 1 functions in the maintenance of cellular survival and genome stability in response to oxidative stress-independent DNA damage

BACKGROUND: DNA damage is generated by various intrinsic and extrinsic sources such as reactive oxygen species (ROS) and environmental mutagens, and causes genomic alterations. DNA damage response (DDR) is activated to induce cell cycle arrest and DNA repair. Oxidation resistance 1 (OXR1) is a prote...

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Detalles Bibliográficos
Autores principales: Matsui, Ako, Hashiguchi, Kazunari, Suzuki, Masao, Zhang-Akiyama, Qiu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653821/
https://www.ncbi.nlm.nih.gov/pubmed/33292791
http://dx.doi.org/10.1186/s41021-020-00168-w

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