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Drug-target interactions prediction using marginalized denoising model on heterogeneous networks
BACKGROUND: Drugs achieve pharmacological functions by acting on target proteins. Identifying interactions between drugs and target proteins is an essential task in old drug repositioning and new drug discovery. To recommend new drug candidates and reposition existing drugs, computational approaches...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653902/ https://www.ncbi.nlm.nih.gov/pubmed/32703151 http://dx.doi.org/10.1186/s12859-020-03662-8 |