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Drug-target interactions prediction using marginalized denoising model on heterogeneous networks

BACKGROUND: Drugs achieve pharmacological functions by acting on target proteins. Identifying interactions between drugs and target proteins is an essential task in old drug repositioning and new drug discovery. To recommend new drug candidates and reposition existing drugs, computational approaches...

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Detalles Bibliográficos
Autores principales: Tang, Chunyan, Zhong, Cheng, Chen, Danyang, Wang, Jianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653902/
https://www.ncbi.nlm.nih.gov/pubmed/32703151
http://dx.doi.org/10.1186/s12859-020-03662-8