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CD4 T-cell immune stimulation of HER2 + breast cancer cells alters response to trastuzumab in vitro
INTRODUCTION: The HER2 + tumor immune microenvironment is composed of macrophages, natural killer cells, and tumor infiltrating lymphocytes, which produce pro-inflammatory cytokines. Determining the effect of T-cells on HER2 + cancer cells during therapy could guide immunogenic therapies that trigge...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654187/ https://www.ncbi.nlm.nih.gov/pubmed/33292267 http://dx.doi.org/10.1186/s12935-020-01625-w |