Cargando…

CD4 T-cell immune stimulation of HER2 + breast cancer cells alters response to trastuzumab in vitro

INTRODUCTION: The HER2 + tumor immune microenvironment is composed of macrophages, natural killer cells, and tumor infiltrating lymphocytes, which produce pro-inflammatory cytokines. Determining the effect of T-cells on HER2 + cancer cells during therapy could guide immunogenic therapies that trigge...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Patrick N., Mansur, Ameer, Dugger, Kari J., Davis, Tessa R., Howard, Grant, Yankeelov, Thomas E., Sorace, Anna G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654187/
https://www.ncbi.nlm.nih.gov/pubmed/33292267
http://dx.doi.org/10.1186/s12935-020-01625-w