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CD4 T-cell immune stimulation of HER2 + breast cancer cells alters response to trastuzumab in vitro

INTRODUCTION: The HER2 + tumor immune microenvironment is composed of macrophages, natural killer cells, and tumor infiltrating lymphocytes, which produce pro-inflammatory cytokines. Determining the effect of T-cells on HER2 + cancer cells during therapy could guide immunogenic therapies that trigge...

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Detalles Bibliográficos
Autores principales:	Song, Patrick N., Mansur, Ameer, Dugger, Kari J., Davis, Tessa R., Howard, Grant, Yankeelov, Thomas E., Sorace, Anna G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654187/ https://www.ncbi.nlm.nih.gov/pubmed/33292267 http://dx.doi.org/10.1186/s12935-020-01625-w

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