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High-Resolution Transcriptomic and Proteomic Profiling of Heterogeneity of Brain-Derived Microglia in Multiple Sclerosis

Microglia are important for central nervous system (CNS) homeostasis and first to respond to tissue damage and perturbations. Microglia are heterogeneous cells; in case of pathology, microglia adopt a range of phenotypes with altered functions. However, how these different microglia subtypes are imp...

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Detalles Bibliográficos
Autores principales: Miedema, Anneke, Wijering, Marion H. C., Eggen, Bart J. L., Kooistra, Susanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654237/
https://www.ncbi.nlm.nih.gov/pubmed/33192299
http://dx.doi.org/10.3389/fnmol.2020.583811

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