Cargando…
High-Resolution Transcriptomic and Proteomic Profiling of Heterogeneity of Brain-Derived Microglia in Multiple Sclerosis
Microglia are important for central nervous system (CNS) homeostasis and first to respond to tissue damage and perturbations. Microglia are heterogeneous cells; in case of pathology, microglia adopt a range of phenotypes with altered functions. However, how these different microglia subtypes are imp...
Autores principales: | Miedema, Anneke, Wijering, Marion H. C., Eggen, Bart J. L., Kooistra, Susanne M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654237/ https://www.ncbi.nlm.nih.gov/pubmed/33192299 http://dx.doi.org/10.3389/fnmol.2020.583811 |
Ejemplares similares
-
Transcriptomic changes in autophagy-related genes are inversely correlated with inflammation and are associated with multiple sclerosis lesion pathology
por: Misrielal, Chairi, et al.
Publicado: (2022) -
Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matter
por: Miedema, Anneke, et al.
Publicado: (2022) -
Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue
por: Alsema, Astrid M., et al.
Publicado: (2020) -
Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes
por: van der Poel, Marlijn, et al.
Publicado: (2019) -
Autophagy in Multiple Sclerosis: Two Sides of the Same Coin
por: Misrielal, Chairi, et al.
Publicado: (2020)