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Role of DNA Methylation and CpG Sites in the Viral Telomerase RNA Promoter during Gallid Herpesvirus 2 Pathogenesis

Gallid herpesvirus type 2 (GaHV-2) is an oncogenic alphaherpesvirus that induces malignant T-cell lymphoma in chicken. GaHV-2 encodes a viral telomerase RNA subunit (vTR) that plays a crucial role in virus-induced tumorigenesis, enhances telomerase activity, and possesses functions independent of th...

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Detalles Bibliográficos
Autores principales:	Pejaković, Srđan, Mbouombouo Mfossa, André Claude, Wiggers, Laëtitia, Kheimar, Ahmed, Coupeau, Damien, Kaufer, Benedikt B., Muylkens, Benoît
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Transformation and Oncogenesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654267/ https://www.ncbi.nlm.nih.gov/pubmed/32967954 http://dx.doi.org/10.1128/JVI.01488-20

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