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AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system

The sudden outbreak of novel coronavirus 2019 (COVID-19) increased the diagnostic burden of radiologists. In the time of an epidemic crisis, we hope artificial intelligence (AI) to reduce physician workload in regions with the outbreak, and improve the diagnosis accuracy for physicians before they c...

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Autores principales: Wang, Bo, Jin, Shuo, Yan, Qingsen, Xu, Haibo, Luo, Chuan, Wei, Lai, Zhao, Wei, Hou, Xuexue, Ma, Wenshuo, Xu, Zhengqing, Zheng, Zhuozhao, Sun, Wenbo, Lan, Lan, Zhang, Wei, Mu, Xiangdong, Shi, Chenxi, Wang, Zhongxiao, Lee, Jihae, Jin, Zijian, Lin, Minggui, Jin, Hongbo, Zhang, Liang, Guo, Jun, Zhao, Benqi, Ren, Zhizhong, Wang, Shuhao, Xu, Wei, Wang, Xinghuan, Wang, Jianming, You, Zheng, Dong, Jiahong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654325/
https://www.ncbi.nlm.nih.gov/pubmed/33199977
http://dx.doi.org/10.1016/j.asoc.2020.106897
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author Wang, Bo
Jin, Shuo
Yan, Qingsen
Xu, Haibo
Luo, Chuan
Wei, Lai
Zhao, Wei
Hou, Xuexue
Ma, Wenshuo
Xu, Zhengqing
Zheng, Zhuozhao
Sun, Wenbo
Lan, Lan
Zhang, Wei
Mu, Xiangdong
Shi, Chenxi
Wang, Zhongxiao
Lee, Jihae
Jin, Zijian
Lin, Minggui
Jin, Hongbo
Zhang, Liang
Guo, Jun
Zhao, Benqi
Ren, Zhizhong
Wang, Shuhao
Xu, Wei
Wang, Xinghuan
Wang, Jianming
You, Zheng
Dong, Jiahong
author_facet Wang, Bo
Jin, Shuo
Yan, Qingsen
Xu, Haibo
Luo, Chuan
Wei, Lai
Zhao, Wei
Hou, Xuexue
Ma, Wenshuo
Xu, Zhengqing
Zheng, Zhuozhao
Sun, Wenbo
Lan, Lan
Zhang, Wei
Mu, Xiangdong
Shi, Chenxi
Wang, Zhongxiao
Lee, Jihae
Jin, Zijian
Lin, Minggui
Jin, Hongbo
Zhang, Liang
Guo, Jun
Zhao, Benqi
Ren, Zhizhong
Wang, Shuhao
Xu, Wei
Wang, Xinghuan
Wang, Jianming
You, Zheng
Dong, Jiahong
author_sort Wang, Bo
collection PubMed
description The sudden outbreak of novel coronavirus 2019 (COVID-19) increased the diagnostic burden of radiologists. In the time of an epidemic crisis, we hope artificial intelligence (AI) to reduce physician workload in regions with the outbreak, and improve the diagnosis accuracy for physicians before they could acquire enough experience with the new disease. In this paper, we present our experience in building and deploying an AI system that automatically analyzes CT images and provides the probability of infection to rapidly detect COVID-19 pneumonia. The proposed system which consists of classification and segmentation will save about 30%–40% of the detection time for physicians and promote the performance of COVID-19 detection. Specifically, working in an interdisciplinary team of over 30 people with medical and/or AI background, geographically distributed in Beijing and Wuhan, we are able to overcome a series of challenges (e.g. data discrepancy, testing time-effectiveness of model, data security, etc.) in this particular situation and deploy the system in four weeks. In addition, since the proposed AI system provides the priority of each CT image with probability of infection, the physicians can confirm and segregate the infected patients in time. Using 1,136 training cases (723 positives for COVID-19) from five hospitals, we are able to achieve a sensitivity of 0.974 and specificity of 0.922 on the test dataset, which included a variety of pulmonary diseases.
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spelling pubmed-76543252020-11-12 AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system Wang, Bo Jin, Shuo Yan, Qingsen Xu, Haibo Luo, Chuan Wei, Lai Zhao, Wei Hou, Xuexue Ma, Wenshuo Xu, Zhengqing Zheng, Zhuozhao Sun, Wenbo Lan, Lan Zhang, Wei Mu, Xiangdong Shi, Chenxi Wang, Zhongxiao Lee, Jihae Jin, Zijian Lin, Minggui Jin, Hongbo Zhang, Liang Guo, Jun Zhao, Benqi Ren, Zhizhong Wang, Shuhao Xu, Wei Wang, Xinghuan Wang, Jianming You, Zheng Dong, Jiahong Appl Soft Comput Article The sudden outbreak of novel coronavirus 2019 (COVID-19) increased the diagnostic burden of radiologists. In the time of an epidemic crisis, we hope artificial intelligence (AI) to reduce physician workload in regions with the outbreak, and improve the diagnosis accuracy for physicians before they could acquire enough experience with the new disease. In this paper, we present our experience in building and deploying an AI system that automatically analyzes CT images and provides the probability of infection to rapidly detect COVID-19 pneumonia. The proposed system which consists of classification and segmentation will save about 30%–40% of the detection time for physicians and promote the performance of COVID-19 detection. Specifically, working in an interdisciplinary team of over 30 people with medical and/or AI background, geographically distributed in Beijing and Wuhan, we are able to overcome a series of challenges (e.g. data discrepancy, testing time-effectiveness of model, data security, etc.) in this particular situation and deploy the system in four weeks. In addition, since the proposed AI system provides the priority of each CT image with probability of infection, the physicians can confirm and segregate the infected patients in time. Using 1,136 training cases (723 positives for COVID-19) from five hospitals, we are able to achieve a sensitivity of 0.974 and specificity of 0.922 on the test dataset, which included a variety of pulmonary diseases. Elsevier B.V. 2021-01 2020-11-10 /pmc/articles/PMC7654325/ /pubmed/33199977 http://dx.doi.org/10.1016/j.asoc.2020.106897 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wang, Bo
Jin, Shuo
Yan, Qingsen
Xu, Haibo
Luo, Chuan
Wei, Lai
Zhao, Wei
Hou, Xuexue
Ma, Wenshuo
Xu, Zhengqing
Zheng, Zhuozhao
Sun, Wenbo
Lan, Lan
Zhang, Wei
Mu, Xiangdong
Shi, Chenxi
Wang, Zhongxiao
Lee, Jihae
Jin, Zijian
Lin, Minggui
Jin, Hongbo
Zhang, Liang
Guo, Jun
Zhao, Benqi
Ren, Zhizhong
Wang, Shuhao
Xu, Wei
Wang, Xinghuan
Wang, Jianming
You, Zheng
Dong, Jiahong
AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system
title AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system
title_full AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system
title_fullStr AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system
title_full_unstemmed AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system
title_short AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system
title_sort ai-assisted ct imaging analysis for covid-19 screening: building and deploying a medical ai system
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654325/
https://www.ncbi.nlm.nih.gov/pubmed/33199977
http://dx.doi.org/10.1016/j.asoc.2020.106897
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