Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis

Mycobacterium chelonae infections usually resolve with adequate therapy. We report the case of an adolescent with a chronic and progressive M chelonae infection refractory to combined antimicrobial and surgical therapy. Whole genome sequence analysis of consecutive isolates distinguished reinfection...

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Autores principales: Flohr, Sarah, Ramette, Alban, Agyeman, Philipp K A, Duppenthaler, Andrea, Scherer, Cordula, Keller, Peter M, Aebi, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654377/
https://www.ncbi.nlm.nih.gov/pubmed/33204765
http://dx.doi.org/10.1093/ofid/ofaa506
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author Flohr, Sarah
Ramette, Alban
Agyeman, Philipp K A
Duppenthaler, Andrea
Scherer, Cordula
Keller, Peter M
Aebi, Christoph
author_facet Flohr, Sarah
Ramette, Alban
Agyeman, Philipp K A
Duppenthaler, Andrea
Scherer, Cordula
Keller, Peter M
Aebi, Christoph
author_sort Flohr, Sarah
collection PubMed
description Mycobacterium chelonae infections usually resolve with adequate therapy. We report the case of an adolescent with a chronic and progressive M chelonae infection refractory to combined antimicrobial and surgical therapy. Whole genome sequence analysis of consecutive isolates distinguished reinfection from recurrence and contributed to the diagnosis of a factitious disorder.
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spelling pubmed-76543772020-11-16 Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis Flohr, Sarah Ramette, Alban Agyeman, Philipp K A Duppenthaler, Andrea Scherer, Cordula Keller, Peter M Aebi, Christoph Open Forum Infect Dis Brief Reports Mycobacterium chelonae infections usually resolve with adequate therapy. We report the case of an adolescent with a chronic and progressive M chelonae infection refractory to combined antimicrobial and surgical therapy. Whole genome sequence analysis of consecutive isolates distinguished reinfection from recurrence and contributed to the diagnosis of a factitious disorder. Oxford University Press 2020-10-22 /pmc/articles/PMC7654377/ /pubmed/33204765 http://dx.doi.org/10.1093/ofid/ofaa506 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Flohr, Sarah
Ramette, Alban
Agyeman, Philipp K A
Duppenthaler, Andrea
Scherer, Cordula
Keller, Peter M
Aebi, Christoph
Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis
title Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis
title_full Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis
title_fullStr Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis
title_full_unstemmed Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis
title_short Recurrent Mycobacterium chelonae Skin Infection Unmasked as Factitious Disorder Using Bacterial Whole Genome Sequence Analysis
title_sort recurrent mycobacterium chelonae skin infection unmasked as factitious disorder using bacterial whole genome sequence analysis
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654377/
https://www.ncbi.nlm.nih.gov/pubmed/33204765
http://dx.doi.org/10.1093/ofid/ofaa506
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