Cannabinoid receptor type 1 antagonist inhibits progression of obesity‐associated nonalcoholic steatohepatitis in a mouse model by remodulating immune system disturbances

SCOPE: This study investigated whether AM251, a cannabinoid receptor type 1 (CB1) antagonist, ameliorates hepatic levels of metabolic abnormalities and inflammatory responses in a murine nonalcoholic steatohepatitis (NASH) model via reversal of disturbances in the immune system. METHODS AND RESULTS:...

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Detalles Bibliográficos
Autores principales: Chen, Chin‐Chang, Chang, Zi‐Yu, Tsai, Fuu‐Jen, Chen, Shih‐Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654409/
https://www.ncbi.nlm.nih.gov/pubmed/32798334
http://dx.doi.org/10.1002/iid3.338

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