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A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics

The enzyme kynurenine 3-monooxygenase (KMO) operates at a critical branch-point in the kynurenine pathway (KP), the major route of tryptophan metabolism. As the KP has been implicated in the pathogenesis of several human diseases, KMO and other enzymes that control metabolic flux through the pathway...

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Detalles Bibliográficos
Autores principales: Maddison, Daniel C., Alfonso-Núñez, Mónica, Swaih, Aisha M., Breda, Carlo, Campesan, Susanna, Allcock, Natalie, Straatman-Iwanowska, Anna, Kyriacou, Charalambos P., Giorgini, Flaviano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654755/
https://www.ncbi.nlm.nih.gov/pubmed/33170836
http://dx.doi.org/10.1371/journal.pgen.1009129