Cargando…
A novel role for kynurenine 3-monooxygenase in mitochondrial dynamics
The enzyme kynurenine 3-monooxygenase (KMO) operates at a critical branch-point in the kynurenine pathway (KP), the major route of tryptophan metabolism. As the KP has been implicated in the pathogenesis of several human diseases, KMO and other enzymes that control metabolic flux through the pathway...
Autores principales: | Maddison, Daniel C., Alfonso-Núñez, Mónica, Swaih, Aisha M., Breda, Carlo, Campesan, Susanna, Allcock, Natalie, Straatman-Iwanowska, Anna, Kyriacou, Charalambos P., Giorgini, Flaviano |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654755/ https://www.ncbi.nlm.nih.gov/pubmed/33170836 http://dx.doi.org/10.1371/journal.pgen.1009129 |
Ejemplares similares
-
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane
por: Swaih, Aisha M., et al.
Publicado: (2022) -
Structural basis of kynurenine 3-monooxygenase inhibition
por: Amaral, Marta, et al.
Publicado: (2013) -
Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease
por: Steinert, Joern R., et al.
Publicado: (2012) -
Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase inhibition?
por: Collier, Mary EW, et al.
Publicado: (2021) -
Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma
por: Sathyasaikumar, Korrapati V., et al.
Publicado: (2022)