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In-vitro inhibitory effect of maternal breastmilk components on rotavirus vaccine replication and association with infant seroconversion to live oral rotavirus vaccine

BACKGROUND: Despite contributing to a significant reduction in rotavirus associated diarrhoea in highly burdened low- and middle-income countries, live attenuated, oral rotavirus vaccines have lower immunogenicity and efficacy in these settings in comparison to more developed countries. Breastmilk h...

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Detalles Bibliográficos
Autores principales: Kazimbaya, Katayi Mwila, Chisenga, Caroline C., Simuyandi, Michelo, Phiri, Cynthia Mubanga, Laban, Natasha Makabilo, Bosomprah, Samuel, Permar, Sallie R., Munsaka, Sody, Chilengi, Roma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654788/
https://www.ncbi.nlm.nih.gov/pubmed/33170860
http://dx.doi.org/10.1371/journal.pone.0240714