Sex differences in viral entry protein expression and host transcript responses to SARS-CoV-2

Epidemiological studies suggest that men exhibit a higher mortality rate to COVID-19 than women, yet the underlying biology is largely unknown. Here, we seek to delineate sex differences in the gene expression of viral entry proteins ACE2 and TMPRSS2, and host transcriptional responses to SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Sun, Mengying, Shankar, Rama, Ko, Meehyun, Chang, Christopher Daniel, Yeh, Shan-Ju, Li, Shilong, Liu, Ke, Zhou, Guoli, Xing, Jing, VanVelsen, Austin, VanVelsen, Tyler, Paithankar, Shreya, Feng, Benjamin Y., Young, Krista, Strug, Michael, Turco, Lauren, Wang, Zichen, Schadt, Eric, Chen, Rong, Li, Xiaohong, Oskotsky, Tomiko, Sirota, Marina, Glicksberg, Benjamin S., Nadkarni, Girish N., Moeser, Adam J., Li, Li, Kim, Seungtaek, Zhou, Jiayu, Chen, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654875/
https://www.ncbi.nlm.nih.gov/pubmed/33173861
http://dx.doi.org/10.21203/rs.3.rs-100914/v2

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