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Drug Inhibition of SARS-CoV-2 Replication in Human Pluripotent Stem Cell–Derived Intestinal Organoids
BACKGROUND AND AIMS: The COVID-19 pandemic has spread worldwide and poses a severe health risk. While most patients present mild symptoms, descending pneumonia can lead to severe respiratory insufficiency. Up to 50% of patients show gastrointestinal symptoms like diarrhea or nausea, intriguingly ass...
Autores principales: | Krüger, Jana, Groß, Rüdiger, Conzelmann, Carina, Müller, Janis A., Koepke, Lennart, Sparrer, Konstantin M.J., Weil, Tatjana, Schütz, Desiree, Seufferlein, Thomas, Barth, Thomas F.E., Stenger, Steffen, Heller, Sandra, Münch, Jan, Kleger, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655023/ https://www.ncbi.nlm.nih.gov/pubmed/33186749 http://dx.doi.org/10.1016/j.jcmgh.2020.11.003 |
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