Direct nose to brain delivery of small molecules: critical analysis of data from a standardized in vivo screening model in rats

The blood–brain barrier (BBB) is often a limiting factor for getting drugs in the brain. Bypassing the BBB by intranasal (IN), or also called nose to brain (NTB), route is an interesting and frequently investigated concept for brain drug delivery. However, despite the body of evidence for IN drug de...

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Detalles Bibliográficos
Autores principales: Dhuyvetter, Deborah, Tekle, Fetene, Nazarov, Maxim, Vreeken, Rob J., Borghys, Herman, Rombouts, Frederik, Lenaerts, Ilse, Bottelbergs, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655051/
https://www.ncbi.nlm.nih.gov/pubmed/33169635
http://dx.doi.org/10.1080/10717544.2020.1837291

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