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Crystal structure-guided design of berberine-based novel chitinase inhibitors
Glycoside hydrolase family 18 (GH18) chitinases play an important role in various organisms ranging from bacteria to mammals. Chitinase inhibitors have potential applications as pesticides, fungicides, and anti-asthmatics. Berberine, a plant-derived isoquinoline alkaloid, was previously reported to...
Autores principales: | Chen, Lei, Zhu, Ling, Chen, Jinli, Chen, Wei, Qian, Xuhong, Yang, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655067/ https://www.ncbi.nlm.nih.gov/pubmed/33167737 http://dx.doi.org/10.1080/14756366.2020.1837123 |
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