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Synthesis, trehalase hydrolytic resistance and inhibition properties of 4- and 6-substituted trehalose derivatives
Although trehalose has recently gained interest because of its pharmaceutical potential, its clinical use is hampered due to its low bioavailability. Hence, hydrolysis-resistant trehalose analogues retaining biological activity could be of interest. In this study, 34 4- and 6-O-substituted trehalose...
Autores principales: | Dhaene, Shari, Van der Eycken, Johan, Beerens, Koen, Franceus, Jorick, Desmet, Tom, Caroen, Jurgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655077/ https://www.ncbi.nlm.nih.gov/pubmed/33164573 http://dx.doi.org/10.1080/14756366.2020.1837125 |
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