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Gb3‐cSrc complex in glycosphingolipid‐enriched microdomains contributes to the expression of p53 mutant protein and cancer drug resistance via β‐catenin–activated RNA methylation

Glucosylceramide synthase (GCS) is a key enzyme catalyzing ceramide glycosylation to generate glucosylceramide (GlcCer), which in turn serves as the precursor for cells to produce glycosphingolipids (GSLs). In cell membranes, GSLs serve as essential components of GSL‐enriched microdomains (GEMs) and...

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Detalles Bibliográficos
Autores principales:	Roy, Kartik R., Uddin, Mohammad B., Roy, Sagor C., Hill, Ronald A., Marshall, John, Li, Yu‐Teh, Chamcheu, Jean Christopher, Lu, Hua, Liu, Yong‐Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655095/ https://www.ncbi.nlm.nih.gov/pubmed/33205006 http://dx.doi.org/10.1096/fba.2020-00044

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