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Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications

The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 µm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue,...

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Detalles Bibliográficos
Autores principales: Rowlands, Christopher J, Bruns, Oliver T, Franke, Daniel, Fukamura, Dai, Jain, Rakesh K, Bawendi, Moungi G, So, Peter T C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOP Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655118/
https://www.ncbi.nlm.nih.gov/pubmed/33191950
http://dx.doi.org/10.1088/1361-6463/ab16b4
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author Rowlands, Christopher J
Bruns, Oliver T
Franke, Daniel
Fukamura, Dai
Jain, Rakesh K
Bawendi, Moungi G
So, Peter T C
author_facet Rowlands, Christopher J
Bruns, Oliver T
Franke, Daniel
Fukamura, Dai
Jain, Rakesh K
Bawendi, Moungi G
So, Peter T C
author_sort Rowlands, Christopher J
collection PubMed
description The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 µm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications.
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spelling pubmed-76551182020-11-12 Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications Rowlands, Christopher J Bruns, Oliver T Franke, Daniel Fukamura, Dai Jain, Rakesh K Bawendi, Moungi G So, Peter T C J Phys D Appl Phys Paper The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 µm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications. IOP Publishing 2019-06-26 2019-04-25 /pmc/articles/PMC7655118/ /pubmed/33191950 http://dx.doi.org/10.1088/1361-6463/ab16b4 Text en © 2019 IOP Publishing Ltd http://creativecommons.org/licenses/by/3.0/ Original content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence (http://creativecommons.org/licenses/by/3.0) . Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
spellingShingle Paper
Rowlands, Christopher J
Bruns, Oliver T
Franke, Daniel
Fukamura, Dai
Jain, Rakesh K
Bawendi, Moungi G
So, Peter T C
Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
title Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
title_full Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
title_fullStr Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
title_full_unstemmed Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
title_short Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
title_sort increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
topic Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655118/
https://www.ncbi.nlm.nih.gov/pubmed/33191950
http://dx.doi.org/10.1088/1361-6463/ab16b4
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