Cargando…

CUEDC1 inhibits epithelial-mesenchymal transition via the TβRI/Smad signaling pathway and suppresses tumor progression in non-small cell lung cancer

Lung cancer remains the most lethal cancer worldwide because of its high metastasis potential. Epithelial-mesenchymal transition (EMT) is known as the first step of the metastasis cascade, but the potential regulatory mechanisms of EMT have not been clearly established. In this study, we first found...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cui, Yue, Song, Yang, Yan, Shi, Cao, Mengru, Huang, Jian, Jia, Dexin, Liu, Yuechao, Zhang, Shuai, Fan, Weina, Cai, Li, Li, Chunhong, Xing, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655170/ https://www.ncbi.nlm.nih.gov/pubmed/33099540 http://dx.doi.org/10.18632/aging.103329

Ejemplares similares

Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling
por: Song, Yang, et al.
Publicado: (2019)

Expression of CUEDC2 in colorectal cancer with different invasion and migration abilities
por: Hu, Shidong, et al.
Publicado: (2019)

CUEDC2 suppresses glioma tumorigenicity by inhibiting the activation of STAT3 and NF-κB signaling pathway
por: Li, Feng, et al.
Publicado: (2017)

CUEDC2 ablation enhances the efficacy of mesenchymal stem cells in ameliorating cerebral ischemia/reperfusion insult
por: Huang, Yan, et al.
Publicado: (2021)

LINC02678 as a Novel Prognostic Marker Promotes Aggressive Non-small-cell Lung Cancer
por: Jia, Dexin, et al.
Publicado: (2021)

Overexpression of CUEDC2 Predicts Poor Prognosis in Ovarian Serous Carcinomas
por: Wang, Aichun, et al.
Publicado: (2015)

PADI4-mediated epithelial-mesenchymal transition in lung cancer cells
por: Liu, Meiyan, et al.
Publicado: (2019)

CUEDC2 modulates cardiomyocyte oxidative capacity by regulating GPX1 stability
por: Jian, Zhao, et al.
Publicado: (2016)

Polydatin ameliorates pulmonary fibrosis by suppressing inflammation and the epithelial mesenchymal transition via inhibiting the TGF-β/Smad signaling pathway
por: Qiu, Yue, et al.
Publicado: (2019)

SIRT7 suppresses the epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis by promoting SMAD4 deacetylation
por: Li, Wenlu, et al.
Publicado: (2018)

CDCA7 promotes TGF‐β‐induced epithelial–mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC
por: Li, Hongyi, et al.
Publicado: (2022)

CUEDC2 down-regulation is associated with tumor growth and poor prognosis in lung adenocarcinoma
por: Sun, Longhua, et al.
Publicado: (2015)

GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition
por: Zhou, Xiao-Ming, et al.
Publicado: (2017)

Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition
por: Sommerova, Lucia, et al.
Publicado: (2017)

Role of Smad3 signaling in the epithelial-mesenchymal transition of the lens epithelium following injury
por: Meng, Fanlan, et al.
Publicado: (2018)

Suppression of Hepatic Epithelial-to-Mesenchymal Transition by Melittin via Blocking of TGFβ/Smad and MAPK-JNK Signaling Pathways
por: Park, Ji-Hyun, et al.
Publicado: (2017)

SMAD4 mutations do not preclude epithelial–mesenchymal transition in colorectal cancer
por: Frey, Patrick, et al.
Publicado: (2021)

Myricetin suppresses TGF-β-induced epithelial-to-mesenchymal transition in ovarian cancer
por: Yang, Hui-Wen, et al.
Publicado: (2023)

Resveratrol suppresses epithelial-to-mesenchymal transition in colorectal cancer through TGF-β1/Smads signaling pathway mediated Snail/E-cadherin expression
por: Ji, Qing, et al.
Publicado: (2015)

Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways
por: Zhou, Xian-Long, et al.
Publicado: (2017)

Downregulation of CUEDC2 prevents doxorubicin-induced cardiotoxicity in H9c2 cells
por: Zhang, Xianpu, et al.
Publicado: (2018)

CUEDC2 Contributes to Cisplatin-Based Chemotherapy Resistance in Ovarian Serious Carcinoma by Regulating p38 MAPK Signaling
por: Wang, Aichun, et al.
Publicado: (2019)

Sprouty2 Suppresses Epithelial-Mesenchymal Transition of Human Lens Epithelial Cells through Blockade of Smad2 and ERK1/2 Pathways
por: Tan, Xuhua, et al.
Publicado: (2016)

Repression of Smad3 by silencing Robo1 attenuates epithelial-mesenchymal transition in tracheobronchial stenosis
por: He, Chunyan, et al.
Publicado: (2023)

miR-484 suppresses proliferation and epithelial–mesenchymal transition by targeting ZEB1 and SMAD2 in cervical cancer cells
por: Hu, Yang, et al.
Publicado: (2017)

A novel EHD1/CD44/Hippo/SP1 positive feedback loop potentiates stemness and metastasis in lung adenocarcinoma
por: Liu, Yuechao, et al.
Publicado: (2022)

Baicalin and puerarin reverse epithelial-mesenchymal transition via the TGF-β1/Smad3 pathway in vitro
por: Wu, Tao, et al.
Publicado: (2018)

Resveratrol inhibits transforming growth factor-β2-induced epithelial-to-mesenchymal transition in human retinal pigment epithelial cells by suppressing the Smad pathway
por: Chen, Ching-Long, et al.
Publicado: (2017)

Lyn regulates epithelial–mesenchymal transition in CS-exposed model through Smad2/3 signaling
por: Liang, Xiaobo, et al.
Publicado: (2019)

RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC
por: Wang, Xiao-Yan, et al.
Publicado: (2017)

CUEDC2 Drives β-Catenin Nuclear Translocation and Promotes Triple-Negative Breast Cancer Tumorigenesis
por: Han, Shuyan, et al.
Publicado: (2022)

Epithelial-mesenchymal transition in primary human bronchial epithelial cells is Smad-dependent and enhanced by fibronectin and TNF-α
por: Câmara, Joana, et al.
Publicado: (2010)

Baicalin inhibits the TGF-β1/p-Smad3 pathway to suppress epithelial-mesenchymal transition-induced metastasis in breast cancer
por: Liu, Ding-Kuo, et al.
Publicado: (2020)

Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial–mesenchymal transition through the TGF-β/Smad pathway
por: Liu, Jianxin, et al.
Publicado: (2020)

AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/Smad3 pathway
por: Deng, Liming, et al.
Publicado: (2023)

Dulaglutide Ameliorates Intrauterine Adhesion by Suppressing Inflammation and Epithelial–Mesenchymal Transition via Inhibiting the TGF-β/Smad2 Signaling Pathway
por: Wang, Yifan, et al.
Publicado: (2023)

Silencing of Long Non-coding RNA SMAD5-AS1 Reverses Epithelial Mesenchymal Transition in Nasopharyngeal Carcinoma via microRNA-195-Dependent Inhibition of SMAD5
por: Li, Siwei, et al.
Publicado: (2019)

Lamp2 inhibits epithelial-mesenchymal transition by suppressing Snail expression in HCC
por: Zheng, Hao, et al.
Publicado: (2018)

ST3GAL5‐catalyzed gangliosides inhibit TGF‐β‐induced epithelial‐mesenchymal transition via TβRI degradation
por: Zhang, Jing, et al.
Publicado: (2022)

TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition
por: Xiao, Yangyang, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_jo1muboql9ahp0qgs917bvri0c