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TREM2 ameliorates neuroinflammatory response and cognitive impairment via PI3K/AKT/FoxO3a signaling pathway in Alzheimer’s disease mice
Triggering receptor expressed on myeloid cells 2 (TREM2) has been shown with a neuroprotective function against inflammation and neuronal injury in Alzheimer’s disease (AD). However, the TREM2 induced anti-inflammatory mechanism is still not well known. In this study it has been demonstrated that th...
Autores principales: | Wang, Yaping, Lin, Yan, Wang, Linhan, Zhan, Hongrui, Luo, Xiaoting, Zeng, Yanyan, Wu, Wen, Zhang, Xingmei, Wang, Fang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655179/ https://www.ncbi.nlm.nih.gov/pubmed/33065553 http://dx.doi.org/10.18632/aging.104104 |
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