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Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells
The age-dependent decline in stem cell function plays a critical role in aging, although the molecular mechanisms remain unclear. PTRF/Cavin-1 is an essential component in the biogenesis and function of caveolae, which regulates cell proliferation, endocytosis, signal transduction and senescence. Th...
Autores principales: | Bai, Lin, Lyu, Ying, Shi, Guiying, Li, Keya, Huang, Yiying, Ma, Yuanwu, Cong, Yu-Sheng, Zhang, Lianfeng, Qin, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655181/ https://www.ncbi.nlm.nih.gov/pubmed/33087586 http://dx.doi.org/10.18632/aging.103729 |
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