Cargando…

Identification of Kinesin Family Member 2A (KIF2A) as a Promising Therapeutic Target for Osteosarcoma

BACKGROUND: Osteosarcoma is known as a type of common human bone malignancy, and more therapeutic targets are still required to combat this disease. In recent years, the involvement of KIF2A in cancer progression has been widely revealed; however, its potential effect on osteosarcoma development rem...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zhe-Xiang, Ren, Shao-Chun, Chang, Zi-Song, Ren, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655250/ https://www.ncbi.nlm.nih.gov/pubmed/33204709 http://dx.doi.org/10.1155/2020/7102757

Ejemplares similares

The primary cilium regulates the expression and subcellular localization of kinesin-3 family member Kif13B
por: Pedersen, LB, et al.
Publicado: (2012)

Novel Dendritic Kinesin Sorting Identified by Different Process Targeting of Two Related Kinesins: KIF21A and KIF21B
por: Marszalek, Joseph R., et al.
Publicado: (1999)

KAP is the neuronal organelle adaptor for Kinesin-2 KIF3AB and KIF3AC
por: Garbouchian, Alex, et al.
Publicado: (2022)

Kinesin Family Member 18A (KIF18A) Contributes to the Proliferation, Migration, and Invasion of Lung Adenocarcinoma Cells In Vitro and In Vivo
por: Chen, Fu-Tao, et al.
Publicado: (2019)

KIF11 and KIF15 mitotic kinesins are potential therapeutic vulnerabilities for malignant peripheral nerve sheath tumors
por: Terribas, Ernest, et al.
Publicado: (2020)

Kinesin Superfamily Member 18B (KIF18B) Promotes Cell Proliferation in Colon Adenocarcinoma
por: Zhao, Fei, et al.
Publicado: (2020)

Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a
por: Sun, Dong, et al.
Publicado: (2017)

Autoinhibition of the kinesin-2 motor KIF17 via dual intramolecular mechanisms
por: Hammond, Jennetta W., et al.
Publicado: (2010)

Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15
por: Malaby, Heidi L.H., et al.
Publicado: (2019)

The role of the Kinesin-13 family protein TbKif13-2 in flagellar length control of Trypanosoma brucei
por: Chan, Kuan Yoow, et al.
Publicado: (2010)

Maternal germline mosaicism of kinesin family member 21A (KIF21A) mutation causes complex phenotypes in a Chinese family with congenital fibrosis of the extraocular muscles
por: Liu, Gang, et al.
Publicado: (2014)

Kinesin Superfamily Member 18B (KIF18B) Promotes Cell Proliferation in Colon Adenocarcinoma [Retraction]
Publicado: (2023)

Kinesin Family of Proteins Kif11 and Kif21B Act as Inhibitory Constraints of Excitatory Synaptic Transmission Through Distinct Mechanisms
por: Swarnkar, Supriya, et al.
Publicado: (2018)

Motor domain-mediated autoinhibition dictates axonal transport by the kinesin UNC-104/KIF1A
por: Cong, Dezi, et al.
Publicado: (2021)

Connecting neurodevelopment to neurodegeneration: a spotlight on the role of kinesin superfamily protein 2A (KIF2A)
por: Ruiz-Reig, Nuria, et al.
Publicado: (2023)

The Kinesin-12 Kif15 is a processive track-switching tetramer
por: Drechsler, Hauke, et al.
Publicado: (2014)

The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma
por: Luo, Weiwei, et al.
Publicado: (2018)

Kinesin Kif2C in regulation of DNA double strand break dynamics and repair
por: Zhu, Songli, et al.
Publicado: (2020)

Altered chemomechanical coupling causes impaired motility of the kinesin-4 motors KIF27 and KIF7
por: Yue, Yang, et al.
Publicado: (2018)

Characterization of Kinesin Family Member 2C as a Proto-Oncogene in Cervical Cancer
por: Yang, Jing, et al.
Publicado: (2022)

KIF3A accelerates KIF3C within the kinesin-2 heterodimer to generate symmetrical phosphate release rates for each processive step
por: Quinn, Sean M., et al.
Publicado: (2020)

Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β2 and Ran-GTP
por: Dishinger, John F., et al.
Publicado: (2010)

Structural insights into human Kif7, a kinesin involved in Hedgehog signalling
por: Klejnot, Marta, et al.
Publicado: (2012)

Motility and microtubule depolymerization mechanisms of the Kinesin-8 motor, KIF19A
por: Wang, Doudou, et al.
Publicado: (2016)

Kinesin-4 KIF21B is a potent microtubule pausing factor
por: van Riel, Wilhelmina E, et al.
Publicado: (2017)

Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin
por: Wang, Weiyi, et al.
Publicado: (2017)

KIF11 Is a Promising Therapeutic Target for Thyroid Cancer Treatment
por: Han, Yue, et al.
Publicado: (2022)

Modulation of estrogen related receptor alpha activity by the kinesin KIF17
por: Seneviratne, AM Pramodh Bandara, et al.
Publicado: (2017)

Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14
por: Benoit, Matthieu P.M.H., et al.
Publicado: (2021)

Identification of Abnormal Spindle Microtubule Assembly as a Promising Therapeutic Target for Osteosarcoma
por: Lin, Peng, et al.
Publicado: (2020)

STARD9/Kif16a is a novel mitotic kinesin and antimitotic target
por: Torres, Jorge Z.
Publicado: (2012)

p53 and Cell Cycle Dependent Transcription of kinesin family member 23 (KIF23) Is Controlled Via a CHR Promoter Element Bound by DREAM and MMB Complexes
por: Fischer, Martin, et al.
Publicado: (2013)

The Overexpression of Kinesin Superfamily Protein 2A (KIF2A) was Associated with the Proliferation and Prognosis of Esophageal Squamous Cell Carcinoma
por: Li, Demao, et al.
Publicado: (2020)

Kinesin family member 11 contributes to the progression and prognosis of human breast cancer
por: Pei, Yuan-Yuan, et al.
Publicado: (2017)

Plk1 regulates the kinesin-13 protein Kif2b to promote faithful chromosome segregation
por: Hood, Emily A., et al.
Publicado: (2012)

Nucleotide-free structures of KIF20A illuminate atypical mechanochemistry in this kinesin-6
por: Ranaivoson, Fanomezana Moutse, et al.
Publicado: (2023)

Silencing KIF18B enhances radiosensitivity: identification of a promising therapeutic target in sarcoma
por: Liu, Wensi, et al.
Publicado: (2020)

The KinI kinesin Kif2a is required for bipolar spindle assembly through a functional relationship with MCAK
por: Ganem, Neil J., et al.
Publicado: (2004)

Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A
por: Xia, Chun-Hong, et al.
Publicado: (2003)

Retracted: KIF11 Is a Promising Therapeutic Target for Thyroid Cancer Treatment
por: Methods in Medicine, Computational and Mathematical
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nb36cto1regcadrt83hvjst7mm