Gelling hypotonic polymer solution for extended topical drug delivery to the eye

Eye-drop formulations should hold as high a concentration of soluble drug in contact with ocular epithelium for as long as possible. However, eye tears and frequent blinking limit drug retention on the ocular surface, and gelling drops typically form clumps that blur vision. Here, we describe a gell...

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Detalles Bibliográficos
Autores principales: Kim, Yoo Chun, Shin, Matthew, Hackett, Sean, Hsueh, Henry T., e Silva, Raquel Lima, Date, Abhijit, Han, Hyounkoo, Kim, Byung-Jin, Xiao, Amy, Kim, Youngwook, Ogunnaike, Laolu, Anders, Nicole M., Hemingway, Avelina, He, Ping, Jun, Albert S., McDonnell, Peter J., Eberhart, Charles, Pitha, Ian, Zack, Donald J., Campochiaro, Peter, Hanes, Justin, Ensign, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655548/
https://www.ncbi.nlm.nih.gov/pubmed/32895514
http://dx.doi.org/10.1038/s41551-020-00606-8

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