Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche

Bone-marrow endothelial cells in the haematopoietic stem-cell niche form a network of blood vessels that regulates blood-cell traffic as well as the maintenance and function of haematopoietic stem and progenitor cells. Here, we report the design and in vivo performance of systemically injected lipid...

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Detalles Bibliográficos
Autores principales: Krohn-Grimberghe, Marvin, Mitchell, Michael J., Schloss, Maximilian J., Khan, Omar F., Courties, Gabriel, Guimaraes, Pedro P.G., Rohde, David, Cremer, Sebastian, Kowalski, Piotr S., Sun, Yuan, Tan, Mingchee, Webster, Jamie, Wang, Karin, Iwamoto, Yoshiko, Schmidt, Stephen P., Wojtkiewicz, Gregory R., Nayar, Ribhu, Frodermann, Vanessa, Hulsmans, Maarten, Chung, Amanda, Hoyer, Friedrich Felix, Swirski, Filip K., Langer, Robert, Anderson, Daniel G., Nahrendorf, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655681/
https://www.ncbi.nlm.nih.gov/pubmed/33020600
http://dx.doi.org/10.1038/s41551-020-00623-7

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