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The Crotoxin:SBA-15 Complex Down-Regulates the Incidence and Intensity of Experimental Autoimmune Encephalomyelitis Through Peripheral and Central Actions
Crotoxin (CTX), the main neurotoxin from Crotalus durissus terrificus snake venom, has anti-inflammatory, immunomodulatory and antinociceptive activities. However, the CTX-induced toxicity may compromise its use. Under this scenario, the use of nanoparticle such as nanostructured mesoporous silica (...
Autores principales: | Sant'Anna, Morena Brazil, Giardini, Aline C., Ribeiro, Marcio A. C., Lopes, Flavia S. R., Teixeira, Nathalia B., Kimura, Louise F., Bufalo, Michelle C., Ribeiro, Orlando G., Borrego, Andrea, Cabrera, Wafa H. K., Ferreira, Julio C. B., Zambelli, Vanessa O., Sant'Anna, Osvaldo A., Picolo, Gisele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655790/ https://www.ncbi.nlm.nih.gov/pubmed/33193433 http://dx.doi.org/10.3389/fimmu.2020.591563 |
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