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Profiling Microglia From Alzheimer’s Disease Donors and Non-demented Elderly in Acute Human Postmortem Cortical Tissue
Microglia are the tissue-resident macrophages of the central nervous system (CNS). Recent studies based on bulk and single-cell RNA sequencing in mice indicate high relevance of microglia with respect to risk genes and neuro-inflammation in Alzheimer’s disease (AD). Here, we investigated microglia t...
Autores principales: | Alsema, Astrid M., Jiang, Qiong, Kracht, Laura, Gerrits, Emma, Dubbelaar, Marissa L., Miedema, Anneke, Brouwer, Nieske, Hol, Elly M., Middeldorp, Jinte, van Dijk, Roland, Woodbury, Maya, Wachter, Astrid, Xi, Simon, Möller, Thomas, Biber, Knut P., Kooistra, Susanne M., Boddeke, Erik W. G. M., Eggen, Bart J. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655794/ https://www.ncbi.nlm.nih.gov/pubmed/33192286 http://dx.doi.org/10.3389/fnmol.2020.00134 |
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