Cargando…

Mitochondria interaction networks show altered topological patterns in Parkinson’s disease

Mitochondrial dysfunction is linked to pathogenesis of Parkinson’s disease (PD). However, individual mitochondria-based analyses do not show a uniform feature in PD patients. Since mitochondria interact with each other, we hypothesize that PD-related features might exist in topological patterns of m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zanin, Massimiliano, Santos, Bruno F. R., Antony, Paul M. A., Berenguer-Escuder, Clara, Larsen, Simone B., Hanss, Zoé, Barbuti, Peter A., Baumuratov, Aidos S., Grossmann, Dajana, Capelle, Christophe M., Weber, Joseph, Balling, Rudi, Ollert, Markus, Krüger, Rejko, Diederich, Nico J., He, Feng Q.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655803/ https://www.ncbi.nlm.nih.gov/pubmed/33173039 http://dx.doi.org/10.1038/s41540-020-00156-4

Ejemplares similares

The Emerging Role of RHOT1/Miro1 in the Pathogenesis of Parkinson's Disease
por: Grossmann, Dajana, et al.
Publicado: (2020)

Variants in Miro1 Cause Alterations of ER-Mitochondria Contact Sites in Fibroblasts from Parkinson’s Disease Patients
por: Berenguer-Escuder, Clara, et al.
Publicado: (2019)

Platelet mitochondrial membrane potential in Parkinson's disease
por: Antony, Paul M A, et al.
Publicado: (2015)

Fibroblast mitochondria in idiopathic Parkinson’s disease display morphological changes and enhanced resistance to depolarization
por: Antony, P. M. A., et al.
Publicado: (2020)

Impaired mitochondrial–endoplasmic reticulum interaction and mitophagy in Miro1-mutant neurons in Parkinson’s disease
por: Berenguer-Escuder, Clara, et al.
Publicado: (2020)

Mitochondrial and Clearance Impairment in p.D620N VPS35 Patient‐Derived Neurons
por: Hanss, Zoé, et al.
Publicado: (2020)

Generation of two induced pluripotent stem cell lines and the corresponding isogenic controls from Parkinson’s disease patients carrying the heterozygous mutations c.1290A > G (p.T351A) or c.2067A > G (p.T610A) in the RHOT1 gene encoding Miro1
por: Chemla, Axel, et al.
Publicado: (2023)

Parkinson’s disease mouse models in translational research
por: Antony, Paul M. A., et al.
Publicado: (2011)

Mutations in RHOT1 Disrupt Endoplasmic Reticulum–Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease
por: Grossmann, Dajana, et al.
Publicado: (2019)

Identification of VIMP as a gene inhibiting cytokine production in human CD4+ effector T cells
por: Capelle, Christophe M., et al.
Publicado: (2021)

Quality Control Strategy for CRISPR-Cas9-Based Gene Editing Complicated by a Pseudogene
por: Hanss, Zoé, et al.
Publicado: (2020)

DJ‐1 depletion prevents immunoaging in T‐cell compartments
por: Zeng, Ni, et al.
Publicado: (2022)

Bidirectional Relation Between Parkinson's Disease and Glioblastoma Multiforme
por: Mencke, Pauline, et al.
Publicado: (2020)

Light microscopy applications in systems biology: opportunities and challenges
por: Antony, Paul Michel Aloyse, et al.
Publicado: (2013)

Using High-Content Screening to Generate Single-Cell Gene-Corrected Patient-Derived iPS Clones Reveals Excess Alpha-Synuclein with Familial Parkinson’s Disease Point Mutation A30P
por: Barbuti, Peter, et al.
Publicado: (2020)

A roadmap towards personalized immunology
por: Delhalle, Sylvie, et al.
Publicado: (2018)

Characterization of Differentiated SH-SY5Y as Neuronal Screening Model Reveals Increased Oxidative Vulnerability
por: Forster, J. I., et al.
Publicado: (2016)

The genetic architecture of mitochondrial dysfunction in Parkinson’s disease
por: Larsen, S. B., et al.
Publicado: (2018)

Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females
por: Capelle, Christophe M., et al.
Publicado: (2023)

Adverse Life Trajectories Are a Risk Factor for SARS-CoV-2 IgA Seropositivity
por: Holuka, Cyrielle, et al.
Publicado: (2021)

Topological structures are consistently overestimated in functional complex networks
por: Zanin, Massimiliano, et al.
Publicado: (2018)

Contributing Factors and Evolution of Impulse Control Disorder in the Luxembourg Parkinson Cohort
por: Binck, Sylvia, et al.
Publicado: (2020)

Corrigendum: Contributing Factors and Evolution of Impulse Control Disorder in the Luxembourg Parkinson Cohort
por: Binck, Sylvia, et al.
Publicado: (2021)

Nanoluciferase-based cell fusion assay for rapid and high-throughput assessment of SARS-CoV-2-neutralizing antibodies in patient samples
por: Meyrath, Max, et al.
Publicado: (2022)

From mouse genetics to systems biology
por: Balling, Rudi
Publicado: (2007)

Gene-corrected p.A30P SNCA patient-derived isogenic neurons rescue neuronal branching and function
por: Barbuti, Peter A., et al.
Publicado: (2021)

LRRK2 in Parkinson's disease – drawing the curtain of penetrance: a commentary
por: Krüger, Rejko
Publicado: (2008)

The Luxembourg Parkinson’s Study: A Comprehensive Approach for Stratification and Early Diagnosis
por: Hipp, Geraldine, et al.
Publicado: (2018)

Enteric neurons from Parkinson’s disease patients display ex vivo aberrations in mitochondrial structure
por: Baumuratov, A. S., et al.
Publicado: (2016)

The extracellular RNA complement of Escherichia coli
por: Ghosal, Anubrata, et al.
Publicado: (2015)

Induced Neural Stem Cells Achieve Long-Term Survival and Functional Integration in the Adult Mouse Brain
por: Hemmer, Kathrin, et al.
Publicado: (2014)

Two type I topoisomerases maintain DNA topology in human mitochondria
por: Menger, Katja E, et al.
Publicado: (2022)

Knockdown of Hsc70-5/mortalin Induces Loss of Synaptic Mitochondria in a Drosophila Parkinson’s Disease Model
por: Zhu, Jun-yi, et al.
Publicado: (2013)

Plasma Amyloid Is Associated with White Matter and Subcortical Alterations and Is Modulated by Age and Seasonal Rhythms in Mouse Lemur Primates
por: Gary, Charlotte, et al.
Publicado: (2018)

Integrating Pathways of Parkinson's Disease in a Molecular Interaction Map
por: Fujita, Kazuhiro A., et al.
Publicado: (2013)

Exploring the contribution of the mitochondrial disulfide relay system to Parkinson’s disease: the PINK1/CHCHD4 interplay
por: Arena, Giuseppe, et al.
Publicado: (2021)

Haploinsufficiency due to a novel ACO2 deletion causes mitochondrial dysfunction in fibroblasts from a patient with dominant optic nerve atrophy
por: Neumann, Marie Anne-Catherine, et al.
Publicado: (2020)

Intronic enhancers of the human SNCA gene predominantly regulate its expression in brain in vivo
por: Cheng, Fubo, et al.
Publicado: (2022)

Dynamic cumulative activity of transcription factors as a mechanism of quantitative gene regulation
por: He, Feng, et al.
Publicado: (2007)

GENESIS OF MITOCHONDRIA IN INSECT FAT BODY
por: Larsen, W. J.
Publicado: (1970)

Cannot write session to /tmp/vufind_sessions/sess_3kmvn3t7rspf14a5nujvg575qj