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Patient-derived ovarian cancer explants: preserved viability and histopathological features in long-term agitation-based cultures

Ovarian carcinoma (OvC) remains a major therapeutic challenge due to its propensity to develop resistance after an initial response to chemotherapy. Interactions of tumour cells with the surrounding microenvironment play a role in tumour survival, invasion capacity and drug resistance. Cancer models...

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Detalles Bibliográficos
Autores principales: Abreu, Sofia, Silva, Fernanda, Mendes, Rita, Mendes, Teresa F., Teixeira, Marta, Santo, Vítor E., Boghaert, Erwin R., Félix, Ana, Brito, Catarina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655823/
https://www.ncbi.nlm.nih.gov/pubmed/33173111
http://dx.doi.org/10.1038/s41598-020-76291-z