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GDF8 Promotes the Cell Invasiveness in Human Trophoblasts by Upregulating the Expression of Follistatin-Like 3 Through the ALK5-SMAD2/3 Signaling Pathway

Growth differentiation factor 8 (GDF8) and its antagonist follistatin-like 3 (FSTL3) are expressed in the placenta during early pregnancy. These two factors may have a role to play in the regulation of normal placentation. However, whether GDF8 can regulate the expression of FSTL3 in human trophobla...

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Detalles Bibliográficos
Autores principales: Xie, Jiamin, Zhu, Hua, Chang, Hsun-Ming, Klausen, Christian, Dong, Minyue, Leung, Peter C. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655915/
https://www.ncbi.nlm.nih.gov/pubmed/33195207
http://dx.doi.org/10.3389/fcell.2020.573781