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GDF8 Promotes the Cell Invasiveness in Human Trophoblasts by Upregulating the Expression of Follistatin-Like 3 Through the ALK5-SMAD2/3 Signaling Pathway
Growth differentiation factor 8 (GDF8) and its antagonist follistatin-like 3 (FSTL3) are expressed in the placenta during early pregnancy. These two factors may have a role to play in the regulation of normal placentation. However, whether GDF8 can regulate the expression of FSTL3 in human trophobla...
Autores principales: | Xie, Jiamin, Zhu, Hua, Chang, Hsun-Ming, Klausen, Christian, Dong, Minyue, Leung, Peter C. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7655915/ https://www.ncbi.nlm.nih.gov/pubmed/33195207 http://dx.doi.org/10.3389/fcell.2020.573781 |
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